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Using resonance Raman cross-section data to estimate the spin state populations of Cytochromes P450
The cytochromes P450 (CYPs) are heme proteins responsible for the oxidation of xenobiotics and pharmaceuticals and the biosynthesis of essential steroid products. In all cases, substrate binding initiates the enzymatic cycle, converting ferric low spin (LS) to high-spin (HS), with the efficiency of...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3891783/ https://ncbi.nlm.nih.gov/pubmed/24443630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jrs.4401 |
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