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Transgenic studies on homeobox genes in nervous system development: spina bifida in Isl1 transgenic mice

To develop in vivo assays for homeobox gene function in neural development, we generated transgenic mice in which the expression of a homeobox gene is altered only within the nervous system, in neurons or neuronal precursor cells. Transgenic expression of Hoxc8 did not result in gross abnormalities,...

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Detalhes bibliográficos
Main Authors: Kappen, Claudia, Yaworsky, Paul J., Muller, Yunhua L., Salbaum, J. Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891654/
https://ncbi.nlm.nih.gov/pubmed/23054727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-012-9643-x
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