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Sequence-Specific Promoter Elements Regulate Temporal-Specific Changes in Chromatin Required for Testis-Specific Activation of the Pgk2 Gene

The phosphoglycerate kinase-2 (Pgk2) gene is regulated in a tissue-, cell type- and developmental stage-specific manner during spermatogenesis and is required for normal sperm motility and fertility in mammals. Activation of Pgk2 transcription is regulated by testis-specific demethylation of DNA and...

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Bibliographic Details
Main Authors: Yang, Zhangsheng, Yoshioka, Hirotaka, McCarrey, John R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891403/
https://ncbi.nlm.nih.gov/pubmed/24000349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/REP-13-0311
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