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A Biodistribution and Toxicity Study of Cobalt Dichloride–N-Acetyl Cysteine (C4) as an Implantable MRI Marker for Prostate Cancer Treatment

PURPOSE: C4, a cobalt dichloride–N-acetyl cysteine complex, is being developed as a positive-signal magnetic resonance imaging (MRI) marker to localize implanted radioactive seeds in prostate brachytherapy. We evaluated the toxicity and biodistribution of C4 in rats with the goal of simulating syste...

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Detalhes bibliográficos
Main Authors: Frank, Steven J., Johansen, Mary J., Martirosyan, Karen, Gagea, Mihai, Van Pelt, Carolyn S., Borne, Agatha, Carmazzi, Yudith, Madden, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891365/
https://ncbi.nlm.nih.gov/pubmed/23092727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2012.09.007
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