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Human kidney-2 cells harbor functional dopamine D1 receptors that require Giα for Gq/11α signaling
A recent study demonstrated that the dopamine D1 receptor (D1R) is nonfunctional in human kidney cells, HK2 cells, in terms of their inability to couple to Gs protein in response to the D1R agonist fenoldopam. Since D1R also couples to Gq protein, we tested whether D1R is functional in HK2 cells in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3891264/ https://ncbi.nlm.nih.gov/pubmed/23698121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00644.2012 |
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