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The NF-κB specific inhibitor DHMEQ prevents thrombus formation in a mouse model of antiphospholipid syndrome

Background: β2-glycoprotein I (β2GPI)-dependent antiphospholipid antibodies (aPLs) are considered to play a pivotal pathogenic role in antiphospholipid syndrome (APS) by inducing the expression of tissue factor, inflammatory cytokines, and chemokines, most of which are dependent upon the NF-κB pathw...

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Détails bibliographiques
Auteurs principaux: Nishimura, Misato, Nii, Tokiko, Trimova, Gulzhan, Miura, Shuhei, Umezawa, Kazuo, Ushiyama, Akira, Kubota, Tetsuo
Format: Artigo
Langue:Inglês
Publié: Society of Diabetic Nephropathy Prevention 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3891145/
https://ncbi.nlm.nih.gov/pubmed/24475437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12860/JNP.2013.19
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