Prolyl isomerase Pin1 and protein kinase HIPK2 cooperate to promote cortical neurogenesis by suppressing Groucho/TLE:Hes1-mediated inhibition of neuronal differentiation

The Groucho/transducin-like Enhancer of split 1 (Gro/TLE1):Hes1 transcriptional repression complex acts in cerebral cortical neural progenitor cells to inhibit neuronal differentiation. The molecular mechanisms that regulate the anti-neurogenic function of the Gro/TLE1:Hes1 complex during cortical n...

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Main Authors: Ciarapica, R, Methot, L, Tang, Y, Lo, R, Dali, R, Buscarlet, M, Locatelli, F, del Sal, G, Rota, R, Stifani, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890956/
https://ncbi.nlm.nih.gov/pubmed/24270405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2013.160
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