Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes

HLA molecules presenting peptides derived from tumor-associated self-antigens (self-TAA) are attractive targets for T-cell–based immunotherapy of cancer. However, detection of such epitopes is hampered by self-tolerance and limitations in the sensitivity of mass spectrometry. Here, we used T cells f...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kumari, Shraddha, Wälchli, Sébastien, Fallang, Lars-Egil, Yang, Weiwen, Lund-Johansen, Fridtjof, Schumacher, Ton N., Olweus, Johanna
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2014
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890872/
https://ncbi.nlm.nih.gov/pubmed/24344295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306549111
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