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Quantum mechanical calculations suggest that lytic polysaccharide monooxygenases use a copper-oxyl, oxygen-rebound mechanism

Lytic polysaccharide monooxygenases (LPMOs) exhibit a mononuclear copper-containing active site and use dioxygen and a reducing agent to oxidatively cleave glycosidic linkages in polysaccharides. LPMOs represent a unique paradigm in carbohydrate turnover and exhibit synergy with hydrolytic enzymes i...

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Detalhes bibliográficos
Main Authors: Kim, Seonah, Ståhlberg, Jerry, Sandgren, Mats, Paton, Robert S., Beckham, Gregg T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890868/
https://ncbi.nlm.nih.gov/pubmed/24344312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316609111
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