Drastic neofunctionalization associated with evolution of the timezyme AANAT 500 Mya

Melatonin (N-acetyl-5-methoxytrypamine) is the vertebrate hormone of the night: circulating levels at night are markedly higher than day levels. This increase is driven by precisely regulated increases in acetylation of serotonin in the pineal gland by arylalkylamine N-acetyltransferase (AANAT), the...

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Autori principali: Falcón, Jack, Coon, Steven L., Besseau, Laurence, Cazaméa-Catalan, Damien, Fuentès, Michaël, Magnanou, Elodie, Paulin, Charles-Hubert, Boeuf, Gilles, Sauzet, Sandrine, Jørgensen, Even H., Mazan, Sylvie, Wolf, Yuri I., Koonin, Eugene V., Steinbach, Peter J., Hyodo, Susumu, Klein, David C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890824/
https://ncbi.nlm.nih.gov/pubmed/24351931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1312634110
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