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Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum

The complement system is a crucial component of the innate immune response against invading bacterial pathogens. The human pathogen Neisseria meningitidis (Nm) is known to possess several mechanisms to evade the complement system, including binding to complement inhibitors. In this study, we describ...

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Auteurs principaux: Del Tordello, Elena, Vacca, Irene, Ram, Sanjay, Rappuoli, Rino, Serruto, Davide
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890809/
https://ncbi.nlm.nih.gov/pubmed/24367091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321556111
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