Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme

APIP, Apaf-1 interacting protein, has been known to inhibit two main types of programmed cell death, apoptosis and pyroptosis, and was recently found to be associated with cancers and inflammatory diseases. Distinct from its inhibitory role in cell death, APIP was also shown to act as a 5-methylthio...

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Detalhes bibliográficos
Main Authors: Kang, Wonchull, Hong, Se Hoon, Lee, Hye Min, Kim, Na Yeon, Lim, Yun Chan, Le, Le Thi My, Lim, Bitna, Kim, Hyun Chul, Kim, Tae Yeon, Ashida, Hiroki, Yokota, Akiho, Hah, Sang Soo, Chun, Keun Ho, Jung, Yong-Keun, Yang, Jin Kuk
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890807/
https://ncbi.nlm.nih.gov/pubmed/24367089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308768111
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