The Reaction of Glucagon with Its Receptor: Evidence for Discrete Regions of Activity and Binding in the Glucagon Molecule

Des-histidine-glucagon (DH-glucagon, glucagon(2-29)) does not activate the glucagon-sensitive adenylate cyclase system present in either liver plasma membranes or in fat-cell “ghosts”, but inhibits the response of these systems to submaximal concentrations of glucagon. DH-glucagon also inhibits, com...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Rodbell, Martin, Birnbaumer, Lutz, Pohl, Stephen L., Sundby, F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1971
Schlagworte:	Biological Sciences: Biochemistry
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389078/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5280527/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.5.909
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