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Altered Methylation of Ribosomal RNA in an Erythromycin-Resistant Strain of Staphylococcus aureus

In certain strains of Staphylococcus aureus, a concentration of erythromycin between 10(-8) and 10(-7) M can induce resistance to concentrations of this drug as high as 10(-4) M. In one such strain studied, S. aureus (1206), N(6)-dimethyladenine is not normally present in 23S rRNA; however, a compou...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lai, C. J., Weisblum, B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1971
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389059/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5279527/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.856
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