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Intrinsic predisposition of naïve cystic fibrosis T cells to differentiate towards a Th17 phenotype

BACKGROUND: Cystic fibrosis (CF) is a complex, multi-system, life-shortening, autosomal recessive disease most common among Caucasians. Pulmonary pathology, the major cause of morbidity and mortality in CF, is characterized by dysregulation of cytokines and a vicious cycle of infection and inflammat...

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Detalhes bibliográficos
Main Authors: Kushwah, Rahul, Gagnon, Stéphane, Sweezey, Neil B
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890528/
https://ncbi.nlm.nih.gov/pubmed/24344776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-14-138
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