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The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.

c-Abl is a nonreceptor tyrosine kinase that is activated by certain DNA-damaging agents. The present studies demonstrate that nuclear c-Abl binds constitutively to the protein tyrosine phosphatase SHPTP1. Treatment with ionizing radiation is associated with c-Abl-dependent tyrosine phosphorylation o...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kharbanda, S, Bharti, A, Pei, D, Wang, J, Pandey, P, Ren, R, Weichselbaum, R, Walsh, C T, Kufe, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38905/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8692915/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.14.6898
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