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Proteomic Analysis and Molecular Modeling Characterize the Iron-Regulatory Protein, Hemojuvelin/Repulsive Guidance Molecule c
Hemojuvelin (HJV) plays a key role in iron metabolism in mammals by regulating expression of the liver-derived hormone, hepcidin, which controls systemic iron uptake and release. Mutations in HJV cause juvenile hemochromatosis, a rapidly progressing iron overload disorder in humans. HJV, also known...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3890427/ https://ncbi.nlm.nih.gov/pubmed/23464809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121845 |
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