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Clinical importance of the drug interaction between statins and CYP3A4 inhibitors: a retrospective cohort study in The Health Improvement Network

OBJECTIVE: To compare the relative hazard of muscle toxicity, renal dysfunction, and hepatic dysfunction associated with the drug interaction between statins and concomitant medications that inhibit the CYP3A4 isoenzyme. BACKGROUND: Although statins provide important clinical benefits related to mit...

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Detalhes bibliográficos
Main Authors: Rowan, Christopher G., Brunelli, Steven M., Munson, Jeffrey, Flory, James, Reese, Peter P., Hennessy, Sean, Lewis, James, Mines, Daniel, Barrett, Jeffrey S., Bilker, Warren, Strom, Brian L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890414/
https://ncbi.nlm.nih.gov/pubmed/22422642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pds.3199
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