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RNA-Dependent RNA Polymerase Activity Associated with Virions and Subviral Particles of Myxoviruses

In vitro RNA synthesis is catalyzed by an enzyme found in purified virions of each of nine influenza strains tested. The extent of [(3)H]UTP incorporation observed is strain dependent, with an obligate requirement for Mn(2+) ions and RNA template. At least 30% of purified product RNA shows resistanc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chow, Nang-Ly, Simpson, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC389035/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4325103/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.4.752
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