EZH2 Protein Expression Associates With the Early Pathogenesis, Tumor Progression and Prognosis of Non-small Cell Lung Carcinoma

PURPOSE: Enhancer of zeste homolog 2 (EZH2) promotes carcinogenesis by epigenetically silencing tumor suppressor genes. We studied EZH2 expression by immunohistochemistry in a large series of non-small cell lung carcinomas (NSCLC) in association with tumor characteristics and patient outcomes. EXPER...

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Bibliographic Details
Main Authors: Behrens, Carmen, Solis, Luisa M., Lin, Heather, Yuan, Ping, Tang, Ximing, Kadara, Humam, Riquelme, Erick, Galindo, Hector, Moran, Cesar A., Kalhor, Neda, Swisher, Stephen G., Simon, George R., Stewart, David J., Lee, J. Jack, Wistuba, Ignacio I.
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890101/
https://ncbi.nlm.nih.gov/pubmed/24097870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-3946
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