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Inhibition of the Metabolism of 25-Hydroxycholecalciferol by Actinomycin D and Cycloheximide

Actinomycin D (or cycloheximide) administered prior to radioactive 25-hydroxycholecalciferol blocks the metabolism of 25-hydroxycholecalciferol to polar metabolites that accumulate in intestinal tissue, while it does not prevent the 25-hydroxylation of vitamin D(3) in the liver. Actinomycin D given...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Tanaka, Y., Deluca, H. F.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1971
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388999/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4322523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.3.605
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