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Concentration-Dependent Opposite Effects of 1-Benzyl-1,2,3,4-tetrahydroisoquinoline on Markers of Apoptosis: In Vitro and Ex Vivo Studies

1-Benzyl-1,2,3,4-tetrahydroisoquinoline (1BnTIQ) was shown to be neurotoxic to the dopaminergic neurons, and thus it was proposed to be an endogenous risk factor leading to Parkinson’s disease. In order to better understand the molecular mechanisms of 1BnTIQ—produced toxicity, we examined the impact...

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Detalhes bibliográficos
Main Authors: Wąsik, Agnieszka, Kajta, Małgorzata, Lenda, Tomasz, Antkiewicz-Michaluk, Lucyna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889680/
https://ncbi.nlm.nih.gov/pubmed/24190811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-013-9436-x
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