Effect of baclofen on morphine-induced conditioned place preference, extinction, and stress-induced reinstatement in chronically stressed mice

RATIONALE AND OBJECTIVE: A stress-induced increase in excitability can result from a reduction in inhibitory neurotransmission. Modulation of gamma-aminobutyric acid (GABA)ergic transmission is an effective treatment for drug seeking and relapse. This study investigated whether baclofen, a GABA(B) r...

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Hlavní autoři: Meng, Shanshan, Quan, Wuxing, Qi, Xu, Su, Zhiqiang, Yang, Shanshan
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2013
Témata:
Original Investigation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889653/
https://ncbi.nlm.nih.gov/pubmed/23892776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3204-8
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