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Defining a role for Sonic hedgehog pathway activation in desmoplastic medulloblastoma by identifying GLI1 target genes

A subgroup of medulloblastomas shows constitutive activation of the Sonic hedgehog pathway with expression of GLI1. We identified the subset of GLI1 transforming target genes specifically expressed in medulloblastomas by comparing GLI1 targets in RK3E cells transformed by GLI1 with the gene expressi...

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Detalhes bibliográficos
Main Authors: Yoon, Joon Won, Gilbertson, Richard, Iannaccone, Stephen, Iannaccone, Philip, Walterhouse, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889649/
https://ncbi.nlm.nih.gov/pubmed/18924150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23929
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