Loss of Feedback Control of Hydroxymethylglutaryl Coenzyme A Reductase in Hepatomas
The feedback response of mevalonate: NADP oxidoreductase (acylating CoA; EC 1.1.1.34) in two varieties of hepatoma has been examined. In marked contrast to the feedback inhibition of this enzyme that is regularly observed in normal liver, the feedback control is completely lost in minimal-deviation...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1971
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5277077/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.2.315 |
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