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Inhibition of CK2 binding to BMPRIa induces C2C12 differentiation into osteoblasts and adipocytes

BMP2 is a growth factor that regulates the cell fate of mesenchymal stem cells into osteoblast and adipocytes. However, the detailed signaling pathways and mechanism are unknown. We previously reported a new interaction of Casein kinase II (CK2) with the BMP receptor type-Ia (BMPRIa) and demonstrate...

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Hlavní autoři: Moseychuk, Oleksandra, Akkiraju, Hemanth, Dutta, Joyita, D’Angelo, Alex, Bragdon, Beth, Duncan, Randall L., Nohe, Anja
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889251/
https://ncbi.nlm.nih.gov/pubmed/23637019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-013-0199-1
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