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Synchronization of Converging Metabolic Pathways: Activation of the Cystathionine γ-Synthase of Neurospora crassa by Methyltetrahydrofolate

Methyltetrahydrofolate synchronizes the activities of the two branches of the pathway of methionine biosynthesis in Neurospora crassa by serving as an essential activator of cystathionine γ-synthase and antagonizing the feedback inhibition of this enzyme by S-adenosylmethionine. Activation is specif...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Selhub, J., Savin, M. A., Sakami, W., Flavin, M.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1971
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388925/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5277076/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.68.2.312
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