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Prostaglandin D(2) pathway upregulation: Relation to asthma severity, control, and T(H)2 inflammation
BACKGROUND: Bronchoalveolar lavage (BAL) fluid prostaglandin D(2) (PGD(2)) levels are increased in patients with severe, poorly controlled asthma in association with epithelial mast cells (MCs). PGD(2), which is generated by hematopoietic prostaglandin D synthase (HPGDS), acts on 3 G protein–coupled...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3889167/ https://ncbi.nlm.nih.gov/pubmed/23506843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.01.035 |
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