Prostaglandin D(2) pathway upregulation: Relation to asthma severity, control, and T(H)2 inflammation

BACKGROUND: Bronchoalveolar lavage (BAL) fluid prostaglandin D(2) (PGD(2)) levels are increased in patients with severe, poorly controlled asthma in association with epithelial mast cells (MCs). PGD(2), which is generated by hematopoietic prostaglandin D synthase (HPGDS), acts on 3 G protein–coupled...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fajt, Merritt L., Gelhaus, Stacy L., Freeman, Bruce, Uvalle, Crystal E., Trudeau, John B., Holguin, Fernando, Wenzel, Sally E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889167/
https://ncbi.nlm.nih.gov/pubmed/23506843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.01.035
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