Linker modification reduced the renal uptake of technetium-99m-labeled Arg-Ala-Asp-conjugated alpha-melanocyte stimulating hormone peptide

The purpose of this study was to examine the biodistribution of (99m)Tc-RAD-Arg-(Arg(11))CCMSH in B16/F1 melanoma-bearing C57 mice to determine whether the replacement of the Lys linker with an Arg linker could decrease the renal uptake of (99m)Tc-RAD-Arg-(Arg(11))CCMSH. (99m)Tc-RAD-Arg-(Arg(11))CCM...

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Main Authors: Yang, Jianquan, Flook, Adam M., Feng, Changjian, Miao, Yubin
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889140/
https://ncbi.nlm.nih.gov/pubmed/24316121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.11.042
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