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PHOSPHODIESTERASE V INHIBITION REDUCES AIRWAY RESPONSIVENESS, BUT DOES NOT IMPROVE THE BENEFICIAL EFFECT OF DEEP INSPIRATION
BACKGROUND: Deep inspirations (DIs) can prevent (bronchoprotection-BP) and reverse (bronchodilation-BD) methacholine (Mch)-induced bronchoconstriction, but this effect is reduced or absent in people with asthma or airways hyperresponsiveness (AHR). The mechanisms of this defect are unknown. OBJECTIV...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888955/ https://ncbi.nlm.nih.gov/pubmed/23860331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000350451 |
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