Age-Associated Defects in EphA2 Signaling Impair the Migration of Human Cardiac Progenitor Cells

BACKGROUND: Aging negatively impacts on the function of resident human cardiac progenitor cells (hCPCs). Effective regeneration of the injured heart requires mobilization of hCPCs to the sites of damage. In the young heart, signaling by the guidance receptor EphA2 in response to the ephrin A1 ligand...

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Hlavní autoři: Goichberg, Polina, Kannappan, Ramaswamy, Cimini, Maria, Bai, Yingnan, Sanada, Fumihiro, Sorrentino, Andrea, Signore, Sergio, Kajstura, Jan, Rota, Marcello, Anversa, Piero, Leri, Annarosa
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888551/
https://ncbi.nlm.nih.gov/pubmed/24141256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.113.004698
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