Repeated Exposure to Lutzomyia intermedia Sand Fly Saliva Induces Local Expression of Interferon-Inducible Genes Both at the Site of Injection in Mice and in Human Blood

During a blood meal, Lutzomyia intermedia sand flies transmit Leishmania braziliensis, a parasite causing tegumentary leishmaniasis. In experimental leishmaniasis, pre-exposure to saliva of most blood-feeding sand flies results in parasite establishment in absence of any skin damages in mice challen...

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Hauptverfasser: Weinkopff, Tiffany, de Oliveira, Camila I., de Carvalho, Augusto M., Hauyon-La Torre, Yazmin, Muniz, Aline C., Miranda, Jose Carlos, Barral, Aldina, Tacchini-Cottier, Fabienne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888461/
https://ncbi.nlm.nih.gov/pubmed/24421912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002627
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