Alterations of Epigenetic Signatures in Hepatocyte Nuclear Factor 4α Deficient Mouse Liver Determined by Improved ChIP-qPCR and (h)MeDIP-qPCR Assays

Hepatocyte nuclear factor 4α (HNF4α) is a liver-enriched transcription factor essential for liver development and function. In hepatocytes, HNF4α regulates a large number of genes important for nutrient/xenobiotic metabolism and cell differentiation and proliferation. Currently, little is known abou...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Qinghao, Lei, Xiaohong, Lu, Hong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888413/
https://ncbi.nlm.nih.gov/pubmed/24427299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084925
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