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Genetic separation of tumor growth and hemorrhagic phenotypes in an estrogen-induced tumor.

Chronic administration of estrogen to the Fischer 344 (F344) rat induces growth of large, hemorrhagic pituitary tumors. Ten weeks of diethylstilbestrol (DES) treatment caused female F344 rat pituitaries to grow to an average of 109.2 +/- 6.3 mg (mean +/- SE) versus 11.3 +/- 1.4 mg for untreated rats...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wendell, D L, Herman, A, Gorski, J
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38884/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755612/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.15.8112
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