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NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation
Maternal-effect mutations in NLRP7 cause rare biparentally inherited hydatidiform moles (BiHMs), abnormal pregnancies containing hypertrophic vesicular trophoblast but no embryo. BiHM trophoblasts display abnormal DNA methylation patterns affecting maternally methylated germline differentially methy...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3888260/ https://ncbi.nlm.nih.gov/pubmed/24105472 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt457 |
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