Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via re-specification of lineage-restricted precursors

Human pluripotent stem cells (hPSCs) represent a promising source of patient-specific cells for disease modeling, drug screens, and cellular therapies. However, the inability to derive engraftable human hematopoietic stem and progenitor (HSPCs) has limited their characterization to in vitro assays....

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Detalhes bibliográficos
Main Authors: Doulatov, Sergei, Vo, Linda T., Chou, Stephanie S., Kim, Peter G., Arora, Natasha, Li, Hu, Hadland, Brandon K., Bernstein, Irwin D., Collins, James J., Zon, Leonard I., Daley, George Q.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888026/
https://ncbi.nlm.nih.gov/pubmed/24094326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2013.09.002
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