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Cytoplasmic Localization and Redox Cysteine Residue of APE1/Ref-1 Are Associated with Its Anti-Inflammatory Activity in Cultured Endothelial Cells

Apurinic/apyrimidinic endonuclease1/redox factor-1 (APE1/ Ref-1) is a multifunctional protein involved in base excision DNA repair and transcriptional regulation of gene expression. APE1/Ref-1 is mainly localized in the nucleus, but cytoplasmic localization has also been reported. However, the funct...

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Detalhes bibliográficos
Main Authors: Park, Myoung Soo, Kim, Cuk-Seong, Joo, Hee Kyoung, Lee, Yu Ran, Kang, Gun, Kim, Soo Jin, Choi, Sunga, Lee, Sang Do, Park, Jin Bong, Jeon, Byeong Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Korea Society for Molecular and Cellular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887937/
https://ncbi.nlm.nih.gov/pubmed/24213673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-0195-6
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