Differential Cell Death and Bcl-2 Expression in Mouse Retina after Glutathione Decrease by Systemic D, L-Buthionine Sulphoximine Administration

Glutathione (GSH) plays a critical role in cellular defense against unregulated oxidative stress in mammalian cells including neurons. We previously demonstrated that GSH decrease using [D, L]-buthionine sulphoximine (BSO) induces retinal cell death, but the underlying mechanisms of this are still u...

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Bibliographic Details
Main Authors: Park, Myoung Hee, Kim, So Yeun, Moon, Chanil, Bae, Young Chul, Moon, Jung-Il, Moon, Cheil
Format: Artigo
Language:Inglês
Published: Korea Society for Molecular and Cellular Biology 2013
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887915/
https://ncbi.nlm.nih.gov/pubmed/23430084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2276-y
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