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Gintonin, a Ginseng-Derived Lysophosphatidic Acid Receptor Ligand, Potentiates ATP-Gated P2X(1) Receptor Channel Currents

Ginseng, the root of Panax ginseng C.A. Meyer, is used as a general tonic. Recently, we isolated a novel ginseng-derived lysophosphatidic acid (LPA) receptor ligand, gintonin. Gintonin activates G protein-coupled LPA receptors with high affinity in cells endogenously expressing LPA receptors, e.g.,...

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Autors principals: Choi, Sun-Hye, Kim, Hyeon-Joong, Kim, Bo-Ra, Shin, Tae-Joon, Hwang, Sung-Hee, Lee, Byung-Hwan, Lee, Sang-Mok, Rhim, Hyewhon, Nah, Seung-Yeol
Format: Artigo
Idioma:Inglês
Publicat: Korea Society for Molecular and Cellular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887903/
https://ncbi.nlm.nih.gov/pubmed/23456336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-013-2293-x
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