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Induction of error-prone repair as a consequence of DNA ligase deficiency in Escherichia coli.

DNA ligase deficiency is shown to induce generalized mutator activity in E. coli. This mutator activity is unaffected by 3 mug/ml of chloramphenicol but is abolished both in lig-recA double mutants and by incubation with 20 mug/ml of chloramphenicol. Dna ligase deficiency is also shown to reactivate...

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Detalhes bibliográficos
Main Authors: Morse, L S, Pauling, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388780/
https://ncbi.nlm.nih.gov/pubmed/1105587
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