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Induction of error-prone repair as a consequence of DNA ligase deficiency in Escherichia coli.
DNA ligase deficiency is shown to induce generalized mutator activity in E. coli. This mutator activity is unaffected by 3 mug/ml of chloramphenicol but is abolished both in lig-recA double mutants and by incubation with 20 mug/ml of chloramphenicol. Dna ligase deficiency is also shown to reactivate...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1975
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC388780/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1105587/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.72.11.4645 |
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