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Absence of an intracellular cobalamin-binding protein in cultured fibroblasts from patients with defective synthesis of 5′-deoxyadenosylcobalamin and methylcobalamin

Three distinct classes of human mutations (cbl A, cbl B, and cbl C) cause defective synthesis of cobalamin (Cbl; vitamin B(12)) coenzymes. Cultured fibroblasts from that unique class (cbl C) deficient in the synthesis of both Cbl coenzymes, 5′-deoxyadenosylcobalamin (AdoCbl) and methylcobalamin (MeC...

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Detalhes bibliográficos
Main Authors: Rosenberg, Leon E., Patel, Lekha, Lilljeqvist, Anne-Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388774/
https://ncbi.nlm.nih.gov/pubmed/16592285
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