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Retroviral Infection of hES Cells Produces Random-like Integration Patterns

Retroviral integration provides us with a powerful tool to realize prolonged gene expressions that are often critical to gene therapy. However, the perturbation of gene regulations in host cells by viral genome integration can lead to detrimental effects, yielding cancer. The oncogenic potential of...

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Bibliografski detalji
Glavni autor: Lim, Kwang-il
Format: Artigo
Jezik:Inglês
Izdano: Korea Society for Molecular and Cellular Biology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887731/
https://ncbi.nlm.nih.gov/pubmed/22526396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-0038-x
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