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Functional HSF1 Requires Aromatic-Participant Interactions in Protecting Mouse Embryonic Fibroblasts against Apoptosis Via G2 Cell Cycle Arrest

The present study highlighted the aromatic-participant interactions in in vivo trimerization of HSF1 and got an insight into the process of HSF1 protecting against apoptosis. In mouse embryonic fibroblasts (MEFs), mutations of mouse HSF1 (W37A, Y60A and F104A) resulted in a loss of trimerization act...

詳細記述

保存先:
書誌詳細
主要な著者: Chang, Ziwei, Lu, Ming, Park, Sung-Min, Park, Hyun-Kyung, Kang, Ho Sung, Pak, Youngshang, Park, Jang-Su
フォーマット: Artigo
言語:Inglês
出版事項: Korea Society for Molecular and Cellular Biology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887730/
https://ncbi.nlm.nih.gov/pubmed/22526392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-2246-9
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