Functional HSF1 Requires Aromatic-Participant Interactions in Protecting Mouse Embryonic Fibroblasts against Apoptosis Via G2 Cell Cycle Arrest

The present study highlighted the aromatic-participant interactions in in vivo trimerization of HSF1 and got an insight into the process of HSF1 protecting against apoptosis. In mouse embryonic fibroblasts (MEFs), mutations of mouse HSF1 (W37A, Y60A and F104A) resulted in a loss of trimerization act...

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Detalhes bibliográficos
Main Authors: Chang, Ziwei, Lu, Ming, Park, Sung-Min, Park, Hyun-Kyung, Kang, Ho Sung, Pak, Youngshang, Park, Jang-Su
Formato: Artigo
Idioma:Inglês
Publicado em: Korea Society for Molecular and Cellular Biology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887730/
https://ncbi.nlm.nih.gov/pubmed/22526392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10059-012-2246-9
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