A Comprehensive Analysis of Common Genetic Variation Around Six Candidate Loci for Intrahepatic Cholestasis of Pregnancy

OBJECTIVES: Intrahepatic cholestasis of pregnancy (ICP) has a complex etiology with a significant genetic component. Heterozygous mutations of canalicular transporters occur in a subset of ICP cases and a population susceptibility allele (p.444A) has been identified in ABCB11. We sought to expand ou...

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Auteurs principaux: Dixon, Peter H, Wadsworth, Christopher A, Chambers, Jennifer, Donnelly, Jennifer, Cooley, Sharon, Buckley, Rebecca, Mannino, Ramona, Jarvis, Sheba, Syngelaki, Argyro, Geenes, Victoria, Paul, Priyadarshini, Sothinathan, Meera, Kubitz, Ralf, Lammert, Frank, Tribe, Rachel M, Ch'ng, Chin Lye, Marschall, Hanns-Ulrich, Glantz, Anna, Khan, Shahid A, Nicolaides, Kypros, Whittaker, John, Geary, Michael, Williamson, Catherine
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2014
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887577/
https://ncbi.nlm.nih.gov/pubmed/24366234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajg.2013.406
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