Uncovering Buffered Pleiotropy: A Genome-Scale Screen for mel-28 Genetic Interactors in Caenorhabditis elegans

mel-28 (maternal-effect-lethal-28) encodes a conserved protein required for nuclear envelope function and chromosome segregation in Caenorhabditis elegans. Because mel-28 is a strict maternal-effect lethal gene, its function is required in the early embryo but appears to be dispensable for larval de...

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Bibliographic Details
Main Authors: Fernandez, Anita G., Mis, Emily K., Lai, Allison, Mauro, Michael, Quental, Angela, Bock, Carly, Piano, Fabio
Format: Artigo
Language:Inglês
Published: Genetics Society of America 2013
Subjects:
Mutant Screen Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887534/
https://ncbi.nlm.nih.gov/pubmed/24281427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.008532
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