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Notch1 Deficiency Results in Decreased Inflammation during Wound Healing and Regulates Vascular Endothelial Growth Factor Receptor-1 and Inflammatory Cytokine Expression in Macrophages
We investigated whether Notch signaling plays a role in regulating macrophage responses to inflammation. In a wound healing assay, macrophage recruitment was decreased in Notch1(+/−) mice, and the wounds were characterized by decreased TNF-α expression. As wound healing progressed, Notch1(+/−) wound...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3887523/ https://ncbi.nlm.nih.gov/pubmed/20739676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000720 |
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