Protective Role of DNJ-27/ERdj5 in Caenorhabditis elegans Models of Human Neurodegenerative Diseases

Aims: Cells have developed quality control systems for protection against proteotoxicity. Misfolded and aggregation-prone proteins, which are behind the initiation and progression of many neurodegenerative diseases (ND), are known to challenge the proteostasis network of the cells. We aimed to explo...

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Autori principali: Muñoz-Lobato, Fernando, Rodríguez-Palero, María Jesús, Naranjo-Galindo, Francisco José, Shephard, Freya, Gaffney, Christopher J., Szewczyk, Nathaniel J., Hamamichi, Shusei, Caldwell, Kim A., Caldwell, Guy A., Link, Chris D., Miranda-Vizuete, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2014
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887457/
https://ncbi.nlm.nih.gov/pubmed/23641861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.5051
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