Protein-energy malnutrition alters IgA responses to rotavirus vaccination and infection but does not impair vaccine efficacy in mice

BACKGROUND: Conflicting evidence links malnutrition to the reduced efficacy of rotavirus vaccines in developing countries, where diarrhea and undernutrition remain leading causes of child deaths. Here, we adapted mouse models of rotavirus vaccination (rhesus rotavirus, RRV), rotavirus infection (EDI...

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Detalhes bibliográficos
Main Authors: Maier, Elizabeth A., Weage, Kristina J., Guedes, Marjorie M, Denson, Lee A., McNeal, Monica M., Bernstein, David I., Moore, Sean R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887447/
https://ncbi.nlm.nih.gov/pubmed/24200975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.10.072
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