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Selective effects of inhibitors of protein synthesis on metabolism of nuclear anc cytoplasmic proteins: evidence for coordinate synthesis of non-histone chromosomal proteins.

We have compared the effects of inhibitors of protein synthesis on the metabolism of nuclear and cytoplasmic proteins of HeLa S-3 cells. L-1-tosylamido-2-phenylethyl chloromethyl ketone, a potent inhibitor of polypeptide chain initiation, was shown to preferentially inhibit the synthesis of cytoplas...

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Detalhes bibliográficos
Main Authors: Vidali, G, Karn, J, Allfrey, V G
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC388739/
https://ncbi.nlm.nih.gov/pubmed/1060125
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