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Mass spectrometry and molecular modeling studies on the inclusion complexes between alendronate and β-cyclodextrin

Complexation of alendronate sodium (AlnNa) with β-cyclodextrin (β-CD) was studied by means of ESI-mass spectrometry. The experimental results show that stable 1:1 inclusion complexes between selected bisphosphonates and β-CD were formed. In addition, complexes with different stoichiometry were obser...

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Bibliografiske detaljer
Main Authors: Biernacka, Joanna, Betlejewska-Kielak, Katarzyna, Witowska-Jarosz, Janina, Kłosińska-Szmurło, Ewa, Mazurek, Aleksander P.
Format: Artigo
Sprog:Inglês
Udgivet: Springer Netherlands 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3887263/
https://ncbi.nlm.nih.gov/pubmed/24431983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10847-013-0315-0
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